Jamestown weed : The poisonous thorn apple or stramonium (Datura stramonium), a rank weed early noticed at Jamestown, Virginia. See Datura.

Example:


Taxonomy
Datura stramonium, Datura, plant, weed, the leaves, the user, scopolamine, unranked, the brain, jimson, free encyclopedia, Datura tatula, atropine, overdose, seeds, cigarettes, experiences, thorn apple.

Defination from the web:
... known by the common names jimson weed, angel's trumpet, devil's weed, thorn apple, tolguacha, Jamestown weed, stinkweed, datura, moonflower ... The James-Town Weed (which resembles the Thorny Apple of Peru, and I take to be the plant so call'd) is supposed to be one of the ...