Harsh a. : Rough; disagreeable; grating

Harsh a. : disagreeable to the touch.

Harsh a. : disagreeable to the taste.

Harsh a. : disagreeable to the ear.

Harsh a. : Unpleasant and repulsive to the sensibilities; austere; crabbed; morose; abusive; abusive; severe; rough.

Harsh a. : Having violent contrasts of color, or of light and shade; lacking in harmony.

Example:
What kind of Harsh chemicals may cause skin cancer?

Taxonomy
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Defination from the web:
Harsh - Definition of Harsh at Dictionary.com a free online dictionary with pronunciation, synonyms, and translation of Harsh. Word of the Day and Crossword Puzzles. ... harsh·er, harsh·est. Unpleasantly coarse and rough to the touch. See Synonyms at rough. Disagreeable to the senses, ...